An introduction to statistical ensembles of closed and open systems, and their use to compute thermodynamic properties from microscopic information. Topics include: classical and quantum statistics, partition functions and their use in the calculation of thermodynamic properties of gases and solids. The course also covers the application of statistical mechanics in reaction-rate theory of chemical reactions. The course also includes advanced topics such as: quantum phenomena (Bose-Einstein condensates), lattice-gas models and statistical mechanics of adsorption, theory of liquids and polymers, and modern unimolecular reaction-rate theories. Students may not retain credit for both CHMI 5576 and either CHMI 4537 or 4576. (lec 3) cr 3.