This course presents recent advances in the characterization of molecular structure and dynamics at a very high time- and spatial- resolution. Particular emphasis is made on modern spectroscopic and spectrometric methods for the study of clusters and biomolecules, including light scattering and size analysis, confocal microscopy, photoacoustic and advanced infrared techniques, circular dichroism, coherent anti- Stokes Raman spectroscopy (CARS), as well as extended X-ray absorption fine structure (EXAFS) and other applications of synchrotron radiation. The course will also cover advances in techniques for the study of adsorbed biomolecules, including scanning probe techniques (STM and AFM), electrchemical methods, and differential scanning calorimetry. PREREQ: CHMI 2517 and CHMI 3536. (lec 3, tut 1.5) cr 3.